Anti-SKA3

Anti-SKA3 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with SKA3 from other sources has not been determined. Protein function: Component of the SKA1 complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. The SKA1 complex is a direct component of the kinetochore-microtubule interface and directly associates with microtubules as oligomeric assemblies. The complex facilitates the processive movement of microspheres along a microtubule in a depolymerization-coupled manner. In the complex, it mediates the microtubule-stimulated oligomerization. [The UniProt Consortium]