Anti-SCD1 (C12H5)

Anti-SCD1 (C12H5)
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
S7900-05B.100 100 µl - -

3 - 19 Werktage*

514,00 €
 
Stearoyl-CoA desaturase 1 (SCD1) is a key lipogenic enzyme found in the endoplasmic reticulum... mehr
Produktinformationen "Anti-SCD1 (C12H5)"
Stearoyl-CoA desaturase 1 (SCD1) is a key lipogenic enzyme found in the endoplasmic reticulum that catalyzes the conversion of palmitoyl-CoA and stearoyl- CoA to palmitoleoyl-CoA (16:1) and oleoyl-CoA (18:1) (1-3). Palmitoleate and oleate are the major components of triglycerides, membrane phospholipids and cholesterol esters (1). SCD1-knockout mice show improved insulin sensitivity and reduced body fat (1). Disruption of SCD1 in mouse brown adipose tissue strengthens insulin signaling and results in increased translocation of Glut4 to plasma membrane and enhanced uptake of glucose (4). Furthermore, SCD1 is essential for the onset of diet-induced body weight gain (1) and insulin resistance in the liver (5). Applications: Suitable for use in Western Blot, Immunoprecipitation, Immunohistochemistry and Immunoflourescence. Other applications not tested. Recommended Dilutions: Western Blot: 1:1000, Immunoprecipitation: 1:50, Immunohistochemistry (Paraffin): 1:200, Immunoflourescence (IF-IC): 1:100, Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Hersteller: United States Biological
Hersteller-Nr: S7900-05B

Eigenschaften

Anwendung: IF, IHC, IP, WB
Antikörper-Typ: Monoclonal
Klon: 9j153(C12H5)
Konjugat: No
Wirt: Rabbit
Reaktivität: Mouse
Immunogen: Synthetic peptide (KLH-coupled) derived from the sequence around Leu35 of mouse SCD1.

Datenbank Information

Handhabung & Sicherheit

Lagerung: -20°C (-20°C Glycerol)
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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