Anti-SARAF

SARAF Antibody is a IgG polyclonal antibody from Assay Genie with reactivity against Human and for use in ELISA applications. SARAF Antibody is a high quality polyclonal antibody for research use only.. Protein function: Negative regulator of store-operated Ca(2+) entry (SOCE) involved in protecting cells from Ca(2+) overfilling. In response to cytosolic Ca(2+) elevation after endoplasmic reticulum Ca(2+) refilling, promotes a slow inactivation of STIM (STIM1 or STIM2)- dependent SOCE activity: possibly act by facilitating the deoligomerization of STIM to efficiently turn off ORAI when the endoplasmic reticulum lumen is filled with the appropriate Ca(2+) levels, and thus preventing the overload of the cell with excessive Ca(2+) ions. [The UniProt Consortium]