Artikelnummer | Größe | Datenblatt | Manual | SDB | Lieferzeit | Menge | Preis |
---|---|---|---|---|---|---|---|
ABE-44-1113-1 | 1 ml | - |
3 - 11 Werktage* |
682,00 €
|
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S-100 is a low-molecular weight protein that is found in Schwann cells, melanocytes, glial cells, histiocytes, lipocytes, skeletal and cardiac muscle, chondrocytes, adipocytes, myoepithelial cells, macrophages, Langerhans cells, dendritic cells, and keratinocytes. S-100 is a useful marker for Schwann cell-derived tumors, as well as a number of well-differentiated tumors of the salivary gland, adipose and cartilaginous tissue. Anti-S-100 is used to detect melanomas, histiocytosis X, malignant peripheral nerve sheath tumors, and clear cell sarcomas. Protein function: Probably acts as a Ca(2+) signal transducer (PubMed:22399290). In response to an increase in intracellular Ca(2+) levels, binds calcium which triggers a conformational change (PubMed:23351007). This conformational change allows interaction of S1001A with specific target proteins, such as TPR-containing proteins, and the modulation of their activity (PubMed:22399290). [The UniProt Consortium]
Schlagworte: | Anti-S100A, Anti-S100A1, Anti-Protein S100-A1, Anti-S-100 protein alpha chain, Anti-S-100 protein subunit alpha, Anti-S100 calcium-binding protein A1, Anti-s-100 Monoclonal Antibody (Clone:IHC100) |
Hersteller: | Abeomics |
Hersteller-Nr: | 44-1113 |
Eigenschaften
Anwendung: | IHC |
Antikörper-Typ: | Monoclonal |
Klon: | IHC100 |
Konjugat: | No |
Wirt: | Mouse |
Spezies-Reaktivität: | human |
Format: | Purified |
Datenbank Information
KEGG ID : | K23758 | Passende Produkte |
UniProt ID : | P23297 | Passende Produkte |
Gene ID | GeneID 6271 | Passende Produkte |
Handhabung & Sicherheit
Lagerung: | -20°C |
Versand: | +4°C (International: +4°C) |
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!