Anti-Prostaglandin E2 (PGE2)

Prostaglandin E2 (PGE2) is derived from PGH2 which in turn is synthesized from arachidonic acid through the cyclooxygenase pathway. Many cell types, such as epithelial cells, fibroblasts, and macrophages produce PGE2. PGE2 possesses vasoactivity, modulates immune funtions, regulates sleep-awake cycles and exhibits many other activities. Applications: Suitable for use in RIA and Inhibition. Other applications not tested. Recommended Dilutions: RIA: 1:25, Inhibition: 130pg of unlabeled PGE2 will result in 50% inhibition of binding of radiolabeled ligand in a standard liquid phase RIA., Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.