Anti-PIST

Anti-PIST Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with PIST from other sources has not been determined. Protein function: Plays a role in intracellular protein trafficking and degradation. May regulate CFTR chloride currents and acid-induced ASIC3 currents by modulating cell surface expression of both channels. May also regulate the intracellular trafficking of the ADR1B receptor. May play a role in autophagy. Overexpression results in CFTR intracellular retention and degradation in the lysosomes. [The UniProt Consortium]