Anti-PGP9.5 UchL1, clone 13C4

Anti-PGP9.5 UchL1, clone 13C4
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
NSJ-V2294SAF-100UG 100 µg - -

3 - 10 Werktage*

752,00 €
 
1 mg/ml in sterile PBS, BSA free, sodium azide free. This antibody specifically reacts with a... mehr
Produktinformationen "Anti-PGP9.5 UchL1, clone 13C4"
1 mg/ml in sterile PBS, BSA free, sodium azide free. This antibody specifically reacts with a protein of 20-30kDa, identified as PGP9.5, also known as ubiquitin carboxyl-terminal hydrolase-1 (UchL1). Initially, PGP9.5 expression in normal tissues was reported in neurons and neuroendocrine cells but later it was found in distal renal tubular epithelium, spermatogonia, Leydig cells, oocytes, melanocytes, prostatic secretory epithelium, ejaculatory duct cells, epididymis, mammary epithelial cells, Merkel cells, and dermal fibroblasts. Furthermore, immunostaining with PGP9.5 antibody has been shown in a wide variety of mesenchymal neoplasms as well. A mutation in PGP9.5 / UchL1 gene is believed to cause a form of Parkinson's disease. Protein function: Ubiquitin-protein hydrolase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. This enzyme is a thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. Also binds to free monoubiquitin and may prevent its degradation in lysosomes. The homodimer may have ATP-independent ubiquitin ligase activity. [The UniProt Consortium]
Schlagworte: Anti-UCHL1, Anti-UCH-L1, Anti-PGP9.5, Anti-PGP 9.5, EC=6.-.-.-, EC=3.4.19.12, Anti-Ubiquitin thioesterase L1, Anti-Neuron cytoplasmic protein 9.5, Anti-Ubiquitin carboxyl-terminal hydrolase isozyme L1, PGP9.5 UchL1 Antibody
Hersteller: NSJ Bioreagents
Hersteller-Nr: V2294SAF

Eigenschaften

Anwendung: WB, IF
Antikörper-Typ: Monoclonal
Klon: 13C4
Konjugat: No
Wirt: Mouse
Spezies-Reaktivität: bovine, dog, guinea pig, human, mouse, swine, rabbit, rat, sheep, zebrafish
Immunogen: Native PGP9.5 / UchL1 protein from brain was used as the immunogen for this antibody.
Format: Purified

Handhabung & Sicherheit

Lagerung: +4°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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