Anti-p21 Cip1 (Ab-145)

Anti-p21 Cip1 (Ab-145)
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
ABD-8B7175.50 50 µg -

3 - 8 Werktage*

230,00 €
 
Custom conjugation services for this antibody as available (eg. labeling of Anti-p21 Cip1... mehr
Produktinformationen "Anti-p21 Cip1 (Ab-145)"
Custom conjugation services for this antibody as available (eg. labeling of Anti-p21 Cip1 (Ab-145) with HRP. Available labels are AF: AF350, AF488, AF555, AF594, AF647, AF680, AF700, AF750. Proteins: HRP, Alkaline Phosphatase, Streptavidin. Tandems: APC, APC/Cy7, APC/AF750, APC/iFluor(TM) 700, APC/iFluor(TM) 750, PE, PE/Cy5, PE/Cy7, PE/AF610, PE/AF700, PE/iFluor(TM) 594, PE/iFluor(TM) 647, PE/iFluor(TM) 700, PE/iFluor(TM) 750, PE/Texas Red(R), PerCP, PerCP/Cy5.5. Small Molecules: Biotin. Traditional Dyes: FITC (Fluorescein), TRITC (Rhodamine), PacBlue, PacOrange, Cy3, Cy5. iFluor: 350, 405, 430, 450, 488, 514, 532, 546, 555, 560, 568, 594, 610, 633, 647, 660, 670, 680, 700, 710, 750, 790, 800, 810, 820, 840, 860, A7. mFluor: UV375, UV460, Violet 450, Violet 500, Violet 510, Violet 540, Blue 570, Green 620, Red 700, Red 780. Protein function: May be involved in p53/TP53 mediated inhibition of cellular proliferation in response to DNA damage. Binds to and inhibits cyclin- dependent kinase activity, preventing phosphorylation of critical cyclin-dependent kinase substrates and blocking cell cycle progression. Functions in the nuclear localization and assembly of cyclin D-CDK4 complex and promotes its kinase activity towards RB1. At higher stoichiometric ratios, inhibits the kinase activity of the cyclin D- CDK4 complex. Inhibits DNA synthesis by DNA polymerase delta by competing with POLD3 for PCNA binding (PubMed:11595739). Plays an important role in controlling cell cycle progression and DNA damage- induced G2 arrest (PubMed:9106657). [The UniProt Consortium]
Schlagworte: Anti-p21, Anti-CAP20, Anti-MDA-6, Anti-CDKN1A, Anti-CDK-interacting protein 1, Anti-Cyclin-dependent kinase inhibitor 1, Anti-Melanoma differentiation-associated protein 6, p21 Cip1 (Ab-145) Antibody
Hersteller: AAT Bioquest
Hersteller-Nr: 8B7175

Eigenschaften

Anwendung: WB, ELISA
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Reaktivität: Human, Mouse
Immunogen: synthetic peptide
Format: Antigen Affinity Purified

Handhabung & Sicherheit

Lagerung: +4°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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