Anti-ORAI1, CT (Transmembrane Protein 142A, TMEM142A, Calcium Release-Activated Calcium Channel Prot

Anti-ORAI1, CT (Transmembrane Protein 142A, TMEM142A, Calcium Release-Activated Calcium Channel Prot
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
O7044-03.100 100 µg - -

3 - 19 Werktage*

582,00 €
 
ORAI1, also known as Transmembrane protein 142A (TMEM142A), is a 32.7 kD multi-pass membrane... mehr
Produktinformationen "Anti-ORAI1, CT (Transmembrane Protein 142A, TMEM142A, Calcium Release-Activated Calcium Channel Prot"
ORAI1, also known as Transmembrane protein 142A (TMEM142A), is a 32.7 kD multi-pass membrane protein belonging to the ORAI family. Antigen stimulation of immune cells triggers Ca2+ entry through Ca2+ release-activated Ca2+ (CRAC) channels. CRAC channels are the main pathway for Ca2+ influx in T-cells and promote the immune response to pathogens by activating the transcription factor NFAT. ORAI1 is a four- transmembrane spanning protein that is an essential component of CRAC. ORAI1 functions as a highly selective Ca2+ plasma membrane channel that is gated through interactions with STIM1, the store-activated endoplasmic reticulum Ca2+ sensor. Defective ORAI1 in humans is the cause of one form of hereditary severe combined immune deficiency (SCID), which results in ablated T-cell Ca2+ entry. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 0.5-1ug/ml, detects a band of approximately 49kD in 49 cell lysates., Optimal dilution to be determined by researcher. Recommended Positive Control: Human Ovary Total Protein Lysate, Storage and Stability: May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add 40-50% glycerol, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Schlagworte: Anti-CRACM1, Anti-Protein orai-1, Anti-Transmembrane protein 142A, Anti-Calcium release-activated calcium channel protein 1
Hersteller: United States Biological
Hersteller-Nr: O7044-03

Eigenschaften

Anwendung: WB
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Reaktivität: Human, Mouse, Rat
Immunogen: A 16 amino acid peptide from near the carboxy terminus of human ORAI1.
Reinheit: Purified by immunoaffinity chromatography
Format: Affinity Purified

Handhabung & Sicherheit

Lagerung: -20°C (-20°C Glycerol)
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
Hier folgen Informationen zur Produktreferenz. mehr
Hier kriegen Sie ein Zertifikat
oder , um Analysenzertifikate anzufordern.
Bewertungen lesen, schreiben und diskutieren... mehr
Kundenbewertungen für "Anti-ORAI1, CT (Transmembrane Protein 142A, TMEM142A, Calcium Release-Activated Calcium Channel Prot"
Bewertung schreiben
oder , um eine Produktbewertung abzugeben.
+ Gratis T-Shirt
Anti-ORAI-1 Anti-ORAI-1
506,00 €
+ Gratis T-Shirt
Anti-ORAI-1 Anti-ORAI-1
132,00 €
+ Gratis T-Shirt
+ Gratis T-Shirt
Zuletzt angesehen