Anti-NMDA NR1 Subunit, clone R1JHL

Anti-NMDA NR1 Subunit antibody is directed against rat NMDA NR1 subunit protein. The antibody was clarified from tissue culture supernatant. Reactivity is expected in rat and mouse. Cross reactivity with NMDA NR1 receptor from other species has not been determined. Protein function: NMDA receptor subtype of glutamate-gated ion channels possesses high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. Plays a key role in synaptic plasticity, synaptogenesis, excitotoxicity, memory acquisition and learning. It mediates neuronal functions in glutamate neurotransmission. Is involved in the cell surface targeting of NMDA receptors. [The UniProt Consortium]