Anti-Natriuretic Peptide Receptor A, NT (NPR1, ANPRA, Atrial natriuretic peptide receptor 1, Atrial

ANPA is a receptor for atrial natriuretic peptide. It exhibits guanylate cyclase activity on binding of ANF. There seem to be at least three ANP receptors: two with guanylate cyclase activity (ANPA and ANPB) and one (ANPC) which is probably responsible for the clearance of ANP from the circulation without a role in signal transduction. This Type I membrane protein belongs to the adenylyl cyclase class-4/guanylyl cyclase family and contains 1 protein kinase-like domain. Applications: Suitable for use in Immunohistochemistry, Immunofluorescence, Recommended Dilution: ELISA: 1:1,000, Immunohistochemistry: 1:50-100, Immunofluorescence: 1:300, Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.