Anti-Napsin A (Lung Adenocarcinoma Marker) Recombinant Mouse Monoclonal Antibody (clone:rNAPSA/1239)

Napsin is a pepsin-like aspartic proteinaseconnected with maturation of surfactant protein B. There are two closely related napsins, napsin A and napsin B. Napsin A is expressed as a single chain protein. Immunohistochemical studies revealed high expression levels of napsin A in human lung and kidney but low expression in spleen. Napsin A is expressed in type II pneumocytes and in adenocarcinomas of lung. The high specificity expression of napsin A in adenocarcinomas of lung is useful to distinguish primary lung adenocarcinomas from adenocarcinomas of other organs. Protein function: May be involved in processing of pneumocyte surfactant precursors. [The UniProt Consortium]