Anti-MYCN

This gene is a member of the MYC family and encodes a protein with a basic helix-loop-helix (bHLH) domain. This protein is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of this gene is associated with a variety of tumors, most notably neuroblastomas. Protein function: Positively regulates the transcription of MYCNOS in neuroblastoma cells. [The UniProt Consortium]