Anti-MINA

Anti-MINA Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with MINA from other sources has not been determined. Protein function: Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. Is involved in the demethylation of trimethylated 'Lys-9' on histone H3 (H3K9me3), leading to an increase in ribosomal RNA expression. Also catalyzes the hydroxylation of 60S ribosomal protein L27a on 'His-39'. May play an important role in cell growth and survival. May be involved in ribosome biogenesis, most likely during the assembly process of pre-ribosomal particles. [The UniProt Consortium]