Anti-Merlin (Ab-518)

Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
ABE-35-1591-50 50 µl -

3 - 11 Werktage*

574,00 €
 
Probable regulator of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway, a signaling pathway that... mehr
Produktinformationen "Anti-Merlin (Ab-518)"
Probable regulator of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway, a signaling pathway that plays a pivotal role in tumor suppression by restricting proliferation and promoting apoptosis. Along with WWC1 can synergistically induce the phosphorylation of LATS1 and LATS2 and can probably function in the regulation of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway. May act as a membrane stabilizing protein. May inhibit PI3 kinase by binding to AGAP2 and impairing its stimulating activity. Protein function: Probable regulator of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway, a signaling pathway that plays a pivotal role in tumor suppression by restricting proliferation and promoting apoptosis. Along with WWC1 can synergistically induce the phosphorylation of LATS1 and LATS2 and can probably function in the regulation of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway. May act as a membrane stabilizing protein. May inhibit PI3 kinase by binding to AGAP2 and impairing its stimulating activity. Suppresses cell proliferation and tumorigenesis by inhibiting the CUL4A-RBX1-DDB1-VprBP/DCAF1 E3 ubiquitin-protein ligase complex. [The UniProt Consortium]
Schlagworte: Anti-NF2, Anti-SCH, Anti-Merlin, Anti-Schwannomin, Anti-Schwannomerlin, Anti-Neurofibromin-2, Anti-Moesin-ezrin-radixin-like protein, Polyclonal Antibody to Merlin (Ab-518)
Hersteller: Abeomics
Hersteller-Nr: 35-1591-50

Eigenschaften

Anwendung: WB, IHC
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Spezies-Reaktivität: human, mouse, rat
Immunogen: Peptide sequence around aa.516~520 (R-L-S-M-E) derived from Human Merlin.
Format: Purified

Handhabung & Sicherheit

Lagerung: +4°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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