Anti-MeCP2

Anti-MeCP2 Antibody was purified by affinity purification. This product reacts with human MeCP2.  Cross reactivity with MeCP2 from species other than human is not known. Protein function: Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Mediates transcriptional repression through interaction with histone deacetylase and the corepressor SIN3A. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). [The UniProt Consortium]