Anti-MCM-BP

Protein function: Associated component of the MCM complex that acts as a regulator of DNA replication. Binds to the MCM complex during late S phase and promotes the disassembly of the MCM complex from chromatin, thereby acting as a key regulator of pre-replication complex (pre-RC) unloading from replicated DNA. Can dissociate the MCM complex without addition of ATP, probably acts by destabilizing interactions of each individual subunits of the MCM complex. Required for sister chromatid cohesion. [The UniProt Consortium]