Anti-LIMD1

Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
G-CAB17585.50 50 µl - -

9 - 20 Werktage*

352,00 €
G-CAB17585.100 100 µl -

9 - 20 Werktage*

448,00 €
 
Protein function: Adapter or scaffold protein which participates in the assembly of numerous... mehr
Produktinformationen "Anti-LIMD1"
Protein function: Adapter or scaffold protein which participates in the assembly of numerous protein complexes and is involved in several cellular processes such as cell fate determination, cytoskeletal organization, repression of gene transcription, cell-cell adhesion, cell differentiation, proliferation and migration. Positively regulates microRNA (miRNA)-mediated gene silencing and is essential for P-body formation and integrity. Acts as a hypoxic regulator by bridging an association between the prolyl hydroxylases and VHL enabling efficient degradation of HIF1A. Acts as a transcriptional corepressor for SNAI1- and SNAI2/SLUG-dependent repression of E-cadherin transcription. Negatively regulates the Hippo signaling pathway and antagonizes phosphorylation of YAP1. Inhibits E2F-mediated transcription, and suppresses the expression of the majority of genes with E2F1-responsive elements. Regulates osteoblast development, function, differentiation and stress osteoclastogenesis. Enhances the ability of TRAF6 to activate adapter protein complex 1 (AP-1) and negatively regulates the canonical Wnt receptor signaling pathway in osteoblasts. May act as a tumor suppressor by inhibiting cell proliferation. [The UniProt Consortium]
Schlagworte: Anti-LIMD1, Anti-LIM domain-containing protein 1, LIMD1 Rabbit pAb
Hersteller: Assay Genie
Hersteller-Nr: CAB17585

Eigenschaften

Anwendung: WB
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Spezies-Reaktivität: human, mouse

Handhabung & Sicherheit

Lagerung: +4°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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