Anti-KLF4 (Krueppel-like Factor 4, Epithelial Zinc Finger Protein EZF, Gut-enriched Krueppel-like Fa

KLF4 is a protein belonging to the krueppel C2H2-type zinc-finger protein family, consisting of three C2H2-type zinc fingers. It functions as a cell cycle checkpoint protein, induces squamous epithelial dysplasia and maintains the integrity of the G2/M checkpoint following DNA damage. KLF4 prevents centrosome amplification following gamma radiation-induced DNA damage and plays a role in the differentiation of epithelial cells and in the development of the skeleton and kidney. Its inactivation leads to bladder carcinogenesis and gastric carcinogenesis. Applications: Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: Western Blot: 1-3ug/ml, Immunohistochemistry (paraffin): 10ug/ml, Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.