Anti-IRS2 / Insulin receptor substrate 2

In 1X PBS, pH 7.4, with 0.09% sodium azide. Insulin receptor substrate 2, a cytoplasmic signaling molecule that mediates effects of insulin, insulin-like growth factor 1, and other cytokines by acting as a molecular adaptor between diverse receptor tyrosine kinases and downstream effectors. This protein is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation, as well as by an interleukin 4 receptor-associated kinase in response to IL4 treatment. Protein function: May mediate the control of various cellular processes by insulin. [The UniProt Consortium]