Anti-IQGA2

IQ motif containing GTPase activating protein 2(IQGAP2) Homo sapiens This gene encodes a member of the IQGAP family. The protein contains three IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. It interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility. [provided by RefSeq, Jul 2008], Protein function: Binds to activated CDC42 and RAC1 but does not seem to stimulate their GTPase activity. Associates with calmodulin. [The UniProt Consortium] Recommended dilutions: WB 1:500-2000 ELISA 1:5000-20000. Cellular localization: cytoplasm,cytosol,microtubule,microvillus,cell surface,actin cytoskeleton,lamellipodium,filopodium,filamentous actin,extracellular exosome,