Anti-Human CD25, PE/Elab Fluor(R) 594 conjugated, clone BC96

CD25 is a 55 kD type I transmembrane glycoprotein also known as the low affinity IL-2 receptor alpha chain or Tac. It is expressed on progenitor lymphocytes, activated T and B cells, and activated monocytes/macrophages. CD25 is also expressed on a subset of non-stimulated CD4+ T cells termed T regulatory cells. CD25 associates with the IL-2 receptor beta (CD122) and common gamma chains (CD132) to form the high affinity IL-2R complex. Protein function: Receptor for interleukin-2. The receptor is involved in the regulation of immune tolerance by controlling regulatory T cells (TREGs) activity. TREGs suppress the activation and expansion of autoreactive T-cells. [The UniProt Consortium]