Anti-HPLN4

function:Binds to hyaluronic acid and may be involved in formation of the extracellular matrix.,similarity:Belongs to the HAPLN family.,similarity:Contains 1 Ig-like C2-type (immunoglobulin-like) domain.,similarity:Contains 2 Link domains.,tissue specificity:Expressed predominantly in brain., Protein function: Essential for the proper localization of brevican (BCAN), mainly as a perineuronal nets (PNNs)-type deposition in the brainstem and cerebellum thereby playing a key role in the formation and structural organization of PNNs. Contributes to the formation and transmission of inhibitory GABAergic synapses between Purkinje cells and deep cerebellar nuclei neurons. [The UniProt Consortium] Recommended dilutions: WB 1:500-2000 ELISA 1:5000-20000. Cellular localization: Secreted, extracellular space, extracellular matrix .