Anti-HLX

HLX (H2.0 Like Homeobox) is a Protein Coding gene. Diseases associated with HLX include Diaphragmatic Hernia-Short Bowel-Asplenia Syndrome and Osteogenesis Imperfecta, Type Vii. Among its related pathways are IL12-mediated signaling events. Gene Ontology (GO) annotations related to this gene include sequence-specific DNA binding. An important paralog of this gene is DBX1. Protein function: Transcription factor required for TBX21/T-bet-dependent maturation of Th1 cells as well as maintenance of Th1-specific gene expression. Involved in embryogenesis and hematopoiesis. [The UniProt Consortium]