Anti-HIF1AN (Hypoxia Inducible Factor 1 alpha Inhibitor, DKFZp762F1811, Factor Inhibiting HIF1, FIH1

Anti-HIF1AN (Hypoxia Inducible Factor 1 alpha Inhibitor, DKFZp762F1811, Factor Inhibiting HIF1, FIH1
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
H3848-85.100 100 µl - -

3 - 19 Werktage*

498,00 €
 
Factor Inhibiting HIF1 (FIH) protein facilitates repression of HIF-1 transcriptional activity by... mehr
Produktinformationen "Anti-HIF1AN (Hypoxia Inducible Factor 1 alpha Inhibitor, DKFZp762F1811, Factor Inhibiting HIF1, FIH1"
Factor Inhibiting HIF1 (FIH) protein facilitates repression of HIF-1 transcriptional activity by binding to VHL, which acts as a transcriptional corepressor. VHL inhibits HIF-1 alpha transactivation function by recruiting histone deacetylases. Involvement of VHL in association with FIH provides a unifying mechanism for the modulation of HIF-1 alpha protein stabilization and transcriptional activation in response to changes in cellular oxygen concentration. Positive Control: Rat astrocytes and C6 and U251 gliomas , Applications: , Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Hersteller: United States Biological
Hersteller-Nr: H3848-85

Eigenschaften

Anwendung: IHC, WB
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Reaktivität: Human
Immunogen: A C-terminal region synthetic peptide made to the human FIH protein sequence (between residues 300 and the C-terminus).
Reinheit: Purified by immunoaffinity chromatography.
Format: Affinity Purified

Datenbank Information

Handhabung & Sicherheit

Lagerung: -20°C (-20°C Glycerol)
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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