| Artikelnummer | Größe | Datenblatt | Manual | SDB | Lieferzeit | Menge | Preis |
|---|---|---|---|---|---|---|---|
| ABE-44-1157-1 | 1 ml | - |
3 - 11 Werktage* |
2.038,00 €
|
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The human Equilibrative Nucleoside Transporter 1 (hENT1) mediates the cellular uptake of physiologic nucleosides, including adenosine, as well as many anti-cancer drugs including gemcitabine, cytarabine, and decitabine. De ciency of hENT1 can lead to resistance of such drugs, and the abundance of hENT1 protein in the plasma membrane is a major indicator of the e ciency and clinical outcome of these anti-cancer nucleosides. Protein function: Mediates both influx and efflux of nucleosides across the membrane (equilibrative transporter). It is sensitive (ES) to low concentrations of the inhibitor nitrobenzylmercaptopurine riboside (NBMPR) and is sodium-independent. It has a higher affinity for adenosine. Inhibited by dipyridamole and dilazep (anticancer chemotherapeutics drugs). [The UniProt Consortium]
| Schlagworte: | Anti-ENT1, Anti-SLC29A1, Anti-Nucleoside transporter, es-type, Anti-Solute carrier family 29 member 1, Anti-Equilibrative nucleoside transporter 1, Anti-Equilibrative NBMPR-sensitive nucleoside transporter, Anti-hENT1 Monoclonal Antibody (Clone:IHC595) |
| Hersteller: | Abeomics |
| Hersteller-Nr: | 44-1157 |
Eigenschaften
| Anwendung: | IHC |
| Antikörper-Typ: | Monoclonal |
| Klon: | IHC595 |
| Konjugat: | No |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
| Format: | Purified |
Datenbank Information
| KEGG ID : | K15014 | Passende Produkte |
| UniProt ID : | Q99808 | Passende Produkte |
| Gene ID | GeneID 2030 | Passende Produkte |
Handhabung & Sicherheit
| Lagerung: | -20°C |
| Versand: | +4°C (International: +4°C) |
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!