Anti-GUCA2B, CT (GUCA2B, Guanylate cyclase activator 2B, Guanylate cyclase C-activating peptide 2, G

Uroguanylin and guanylin (GUCA2A, MIM 139392), peptide homologs of the bacterial heat-stable enterotoxins (e.g., the E. coli ST toxin, STa), are endogenous activators of the guanylate cyclase-2C receptor (GUCY2C, MIM 601330), which synthesizes cyclic GMP (cGMP), a key component of several intracellular signal transduction pathways. Applications: Suitable for use in Western Blot, ELISA, Recommended Dilution: ELISA: 1:1,000, Western Blot: 1:100-500, Storage and Stability: Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. , , Note: Applications are based on unconjugated antibody.