Anti-Glycophorin A / CD235a (Erythrocyte Marker) (clone: GYPA/1725R) (recombinant rabbit monoclonal)

Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
ABE-12-1024-20 20 µg -

3 - 11 Werktage*

373,00 €
 
Recognizes a sialoglycoprotein of 39kDa, identified as glycophorin A (GPA). It is present on red... mehr
Produktinformationen "Anti-Glycophorin A / CD235a (Erythrocyte Marker) (clone: GYPA/1725R) (recombinant rabbit monoclonal)"
Recognizes a sialoglycoprotein of 39kDa, identified as glycophorin A (GPA). It is present on red blood cells (RBC) and erythroid precursor cells. It has been shown that glycophorin acts as the receptor for Sandei virus and parvovirus. Glycophorins A (GPA) and B (GPB), which are single, trans-membrane sialoglycoproteins. GPA is the carrier of blood group M and N specificities, while GPB accounts for S and U specificities. GPA and GPB provide the cells with a large mucin like surface and it has been suggested this provides a barrier to cell fusion, so minimizing aggregation between red blood cells in the circulation. Protein function: Glycophorin A is the major intrinsic membrane protein of the erythrocyte. The N-terminal glycosylated segment, which lies outside the erythrocyte membrane, has MN blood group receptors. Appears to be important for the function of SLC4A1 and is required for high activity of SLC4A1. May be involved in translocation of SLC4A1 to the plasma membrane. Is a receptor for influenza virus. Is a receptor for Plasmodium falciparum erythrocyte-binding antigen 175 (EBA-175), binding of EBA-175 is dependent on sialic acid residues of the O-linked glycans. Appears to be a receptor for Hepatitis A virus (HAV). [The UniProt Consortium]
Schlagworte: Anti-GPA, Anti-GYPA, Anti-PAS-2, Anti-CD235a, Anti-Glycophorin-A, Anti-MN sialoglycoprotein, Anti-Sialoglycoprotein alpha, Recombinant Rabbit Monoclonal Antibody to Glycophorin A / CD235a (Erythrocyte Marker)(Clone : GYPA/1725R)
Hersteller: Abeomics
Hersteller-Nr: 12-1024-20

Eigenschaften

Anwendung: FC, IF, IHC
Antikörper-Typ: Monoclonal
Klon: GYPA/1725R
Konjugat: No
Wirt: Rabbit
Spezies-Reaktivität: human
Immunogen: Recombinant human full-length Glycophorin A protein
Format: Purified

Handhabung & Sicherheit

Lagerung: +4°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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