Anti-FSH-Receptor (Ovarian Marker) Monoclonal Antibody (Clone: FSHR/1400)

Follicle-stimulating hormone receptor (FSHR) is a 695 amino acid G protein coupled receptor. FSH binds to the receptor in a hand-clasp fashion via its a condition characterized by the presence of multiple serous and hemorrhagic follicular cysts lined by luteinized cells. Protein function: G protein-coupled receptor for follitropin, the follicle- stimulating hormone (PubMed:11847099, PubMed:24058690, PubMed:24692546). Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways (PubMed:24058690). [The UniProt Consortium]