Anti-FADS2, NT (FADS2, Fatty acid desaturase 2, Delta(6) fatty acid desaturase)

The protein encoded by this gene is a member of the fatty acid desaturase (FADS) gene family. Desaturase enzymes regulate unsaturation of fatty acids through the introduction of double bonds between defined carbons of the fatty acyl chain. FADS family members are considered fusion products composed of an N-terminal cytochrome b5-like domain and a C-terminal multiple membrane-spanning desaturase portion, both of which are characterized by conserved histidine motifs. This gene is clustered with family members FADS1 and FADS2 at 11q12-q13.1, this cluster is thought to have arisen evolutionarily from gene duplication based on its similar exon/intron organization. Applications: Suitable for use in Western Blot, Immunohistochemistry, Flow Cytometry, Immunofluorescence and ELISA. Other applications have not been tested. Recommended Dilution: Western Blot: 1:1000, Immunohistochemistry (FFPE): 1:10-1:50, Flow Cytometry: 1:25, Immunofluorescence: 1:10-1:50, Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.