Anti-ESET (SETB, Histone H3-K9 methyltransferase-4, H3-K9-HMTase-4)

Anti-ESET (SETB, Histone H3-K9 methyltransferase-4, H3-K9-HMTase-4)
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
600-401-689 100 µg - -

6 - 10 Werktage*

684,00 €
 
Protein function: Histone methyltransferase that specifically trimethylates 'Lys-9' of histone... mehr
Produktinformationen "Anti-ESET (SETB, Histone H3-K9 methyltransferase-4, H3-K9-HMTase-4)"
Protein function: Histone methyltransferase that specifically trimethylates 'Lys-9' of histone H3. H3 'Lys-9' trimethylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 (CBX1, CBX3 and/or CBX5) proteins to methylated histones. Mainly functions in euchromatin regions, thereby playing a central role in the silencing of euchromatic genes. H3 'Lys-9' trimethylation is coordinated with DNA methylation. Probably forms a complex with MBD1 and ATF7IP that represses transcription and couples DNA methylation and histone 'Lys-9' trimethylation. Its activity is dependent on MBD1 and is heritably maintained through DNA replication by being recruited by CAF-1. SETDB1 is targeted to histone H3 by TRIM28/TIF1B, a factor recruited by KRAB zinc-finger proteins. [The UniProt Consortium]
Schlagworte: Anti-ESET, Anti-SETDB1, Anti-KIAA0067, EC=2.1.1.43, Anti-H3-K9-HMTase 4, Anti-SET domain bifurcated 1, Anti-Lysine N-methyltransferase 1E, Anti-Histone H3-K9 methyltransferase 4, Anti-ERG-associated protein with SET domain
Hersteller: Rockland Immunochemicals
Hersteller-Nr: 600-401-689

Eigenschaften

Anwendung: ELISA, IHC, WB
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Spezies-Reaktivität: human
Immunogen: synthetic peptide corresponding to amino acids 1058-1075 of human ESET
MW: 170 kD
Format: Affinity Purified

Handhabung & Sicherheit

Lagerung: -20°C
Versand: -20°C (International: -20°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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