Anti-EphA10

Ephrin receptors, the largest subfamily of receptor tyrosine kinases (RTKs), and their ephrin ligands are important mediators of cell-cell communication regulating cell attachment, shape, and mobility in neuronal and epithelial cells (Aasheim et al., 2005 [PubMed 15777695]). See MIM 179610 for additional background on Eph receptors and ephrins.[supplied by OMIM, Mar 2008], Protein function: Receptor for members of the ephrin-A family. Binds to EFNA3, EFNA4 and EFNA5. [The UniProt Consortium] Recommended dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.. Cellular localization: [Isoform 1]: Cell membrane , Single-pass type I membrane protein ., [Isoform 3]: Cell membrane , Single-pass type I membrane protein ., [Isoform 2]: Secreted .