Anti-DTX3L/BBAP

Anti-DTX3L/BBAP
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
A300-833A-T 10 µl (10 µg) -

2 - 8 Werktage*

164,00 €
A300-833A 100 µl (100 µg) -

2 - 8 Werktage*

588,00 €
 
Protein function: Ubiquitin ligase that mediates monoubiquitination of 'Lys-91' of histone H4... mehr
Produktinformationen "Anti-DTX3L/BBAP"
Protein function: Ubiquitin ligase that mediates monoubiquitination of 'Lys-91' of histone H4 (H4K91ub1), in response to DNA damage. Protects cells exposed to DNA-damaging agents. The exact role of H4K91ub1 in DNA damage response is still unclear but it may function as a licensing signal for additional histone H4 post- translational modifications such as H4 'Lys-20' methylation (H4K20me). Involved in the recruitment of 53BP1/TP53BP1 to sites of DNA damage by mediating H4K91ub1 formation. In concert with PARP9, plays a role in PARP1-dependent DNA damage repair. PARP1- dependent PARP9-DTX3L-mediated ubiquitination promotes the rapid and specific recruitment of 53BP1/TP53BP1, UIMC1/RAP80, and BRCA1 to DNA damage sites. [The UniProt Consortium]
Schlagworte: Anti-BBAP, Anti-DTX3L, Anti-Rhysin2, Anti-Rhysin-2, Anti-Protein deltex-3-like, Anti-E3 ubiquitin-protein ligase DTX3L, Anti-B-lymphoma- and BAL-associated protein, Anti-RING-type E3 ubiquitin transferase DTX3L
Hersteller: Bethyl Laboratories
Hersteller-Nr: A300-833A

Eigenschaften

Anwendung: WB, IP
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Spezies-Reaktivität: human (Erwartet: gorilla, chimpanzee, white-tufted-ear marmoset)
Immunogen: synthetic peptide. The epitope recognized by A300-833A-T maps to a region between residue 75 and 125 of human Deltex 3-Like Protein (B-Lymphoma- and BAL-Associated Protein) using the numbering given in entry NP_612144.1 (GeneID 151636).
Format: Antigen Affinity Purified

Handhabung & Sicherheit

Lagerung: +4°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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