Anti-Doppel / PRND

0.5mg/ml if reconstituted with 0.2ml sterile DI water. Prion protein 2 (dublet), also known as PRND, or Doppel protein, is a protein which in humans is encoded by the PRND gene. It is mapped to 20p13. This gene is found on chromosome 20, approximately 20 kbp downstream of the gene encoding cellular prion protein, to which it is biochemically and structurally similar. The protein encoded by this gene is a membrane glycosylphosphatidylinositol-anchored glycoprotein that is found predominantly in testis. Mutations in this gene may lead to neurological disorders. Protein function: Required for normal acrosome reaction and for normal male fertility. Can bind Cu(2+) (PubMed:15218028, PubMed:20411530). [The UniProt Consortium]