Anti-Cytochrome P450 26A1

Anti-Cytochrome P450 26A1
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
ABD-8C12254.50 50 µg -

3 - 8 Werktage*

230,00 €
 
Custom conjugation services for this antibody as available (eg. labeling of Anti-Cytochrome P450... mehr
Produktinformationen "Anti-Cytochrome P450 26A1"
Custom conjugation services for this antibody as available (eg. labeling of Anti-Cytochrome P450 26A1 with HRP. Available labels are AF: AF350, AF488, AF555, AF594, AF647, AF680, AF700, AF750. Proteins: HRP, Alkaline Phosphatase, Streptavidin. Tandems: APC, APC/Cy7, APC/AF750, APC/iFluor(TM) 700, APC/iFluor(TM) 750, PE, PE/Cy5, PE/Cy7, PE/AF610, PE/AF700, PE/iFluor(TM) 594, PE/iFluor(TM) 647, PE/iFluor(TM) 700, PE/iFluor(TM) 750, PE/Texas Red(R), PerCP, PerCP/Cy5.5. Small Molecules: Biotin. Traditional Dyes: FITC (Fluorescein), TRITC (Rhodamine), PacBlue, PacOrange, Cy3, Cy5. iFluor: 350, 405, 430, 450, 488, 514, 532, 546, 555, 560, 568, 594, 610, 633, 647, 660, 670, 680, 700, 710, 750, 790, 800, 810, 820, 840, 860, A7. mFluor: UV375, UV460, Violet 450, Violet 500, Violet 510, Violet 540, Blue 570, Green 620, Red 700, Red 780. Protein function: A cytochrome P450 monooxygenase involved in the metabolism of all-trans retinoic acid (atRA), a signaling molecule that binds to retinoic acid receptors and regulates gene transcription. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR, NADPH- ferrihemoprotein reductase). Catalyzes the hydroxylation of carbon hydrogen bonds of atRA primarily at C-4 and C-18. Has no activity toward 9-cis and 13-cis retinoic acid stereoisomers (PubMed:22020119, PubMed:9228017, PubMed:9716180). May play a role in the oxidative metabolism of xenobiotics such as tazarotenic acid (PubMed:26937021). [The UniProt Consortium]
Schlagworte: Anti-CYP26, Anti-hP450RAI, Anti-Cytochrome P450RAI, Anti-Cytochrome P450 26A1, Anti-Retinoic acid 4-hydroxylase, Anti-Retinoic acid-metabolizing cytochrome, Anti-Cytochrome P450 retinoic acid-inactivating 1, Cytochrome P450 26A1 Antibody
Hersteller: AAT Bioquest
Hersteller-Nr: 8C12254

Eigenschaften

Anwendung: WB, ELISA
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Reaktivität: Human, Mouse
Immunogen: synthetic peptide
Format: Antigen Affinity Purified

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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