Anti-CELSR3

This gene belongs to the flamingo subfamily, which is included in the cadherin superfamily. The flamingo cadherins consist of nonclassic-type cadherins that do not interact with catenins. They are plasma membrane proteins containing seven epidermal growth factor-like repeats, nine cadherin domains and two laminin A G-type repeats in their ectodomain. They also have seven transmembrane domains, a characteristic feature of their subfamily. The encoded protein may be involved in the regulation of contact-dependent neurite growth and may play a role in tumor formation. [provided by RefSeq, Jun 2013], Protein function: Receptor that may have an important role in cell/cell signaling during nervous system formation. [The UniProt Consortium] Recommended dilutions: Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.. Cellular localization: Cell membrane, Multi-pass membrane protein.