Anti-CD40, clone 2Q1632

Anti-CD40, clone 2Q1632
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
C2392-17A.500 500 µg - -

3 - 19 Werktage*

451,00 €
 
CD40 is a type I cell surface protein belonging to the tumor necrosis factor superfamily of cell... mehr
Produktinformationen "Anti-CD40, clone 2Q1632"
CD40 is a type I cell surface protein belonging to the tumor necrosis factor superfamily of cell surface receptors. In mice it is expressed on B lineage cells, follicular dendritic cells, thymic epithelium, and interdigitating cells in the T-cell zone of secondary lymphoid organs. CD40 first becomes detectable on a subset of small pre-B II cells in bone marrow, with the levels of CD40 expression increasing thereafter during B-cell maturation. Immature B cells (IgM+IgDloB220lo) express intermediate levels of CD40, whereas mature B cells (IgM+IgDhiB220hi) express high levels. CD40 has a central role in B cell growth and differentiation, and signalling through CD40 in combination with IL-4 reportedly induces immunoglobulin isotype switching and secretion of IgE. The agonistic monoclonal antibody closely resembles gp39/CD40 ligand in its ability to stimulate proliferation of small, resting B lymphocytes in the absence of other cofactors. RESEARCH APPLICATIONS  Flow cytometry 2,  Immunoprecipitation 2,  In vitro induction of proliferation of mature B lymphocytes 2, Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Store at -20°C or colder. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Hersteller: United States Biological
Hersteller-Nr: C2392-17A

Eigenschaften

Anwendung: FC, IP
Antikörper-Typ: Monoclonal
Klon: 5K254
Konjugat: No
Wirt: Rat
Spezies-Reaktivität: mouse
Format: Purified

Datenbank Information

Handhabung & Sicherheit

Lagerung: -20°C (frozen cool packs!)
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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