Anti-CD253 (human), Biotin Conjugated Clone B-T24 [Mouse]

Specificity: Recognises the TRAIL, APO2L antigen, a 32 kDa protein, Format: Phosphate-buffered saline. With 1% BSA and 0,09% Sodium Azide, Working Dilution: The suggested coating concentration range below should be optimised by each laboratory for each application. ELISA: 0,05-0,5µg/ml, Storage: Store at +2-8°C for 12 months. For longer storage, freeze aliquots, Application Notes: This Antibody can be used as Detection in a human **** sandwich Immunoassay to detect human **** in combination with human **** Capture Antibody (Cat n° ***.***.***). The suggested coating concentration range below should be optimised by each laboratory for each application. Protein function: Cytokine that binds to TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and possibly also to TNFRSF11B/OPG (PubMed:26457518, PubMed:10549288). Induces apoptosis. Its activity may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and TNFRSF11B/OPG that cannot induce apoptosis. [The UniProt Consortium]