Anti-CD25 (Tac antigen, p55, Interleukin 2 Receptor alpha, IL2Ra, T Cell Growth Factor Receptor), FI

Anti-CD25 (Tac antigen, p55, Interleukin 2 Receptor alpha, IL2Ra, T Cell Growth Factor Receptor), FI
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
C2275-89B.100 100 µg - -

3 - 19 Werktage*

364,00 €
C2275-89B.500 500 µg - -

3 - 19 Werktage*

591,00 €
 
The IL-2 receptor (IL-2R) exists in three alternative forms made up from the individual... mehr
Produktinformationen "Anti-CD25 (Tac antigen, p55, Interleukin 2 Receptor alpha, IL2Ra, T Cell Growth Factor Receptor), FI"
The IL-2 receptor (IL-2R) exists in three alternative forms made up from the individual components of CD25, CD122, and CD132. CD25 represents the low affinity alpha chain of the IL-2R, a type I transmembrane glycoprotein containing two CCP domains. It is rich in O-linked carbohydrates and has a short cytoplasmic tail. CD25 is expressed on activated T cells, B cells, NK cells and monocytes of all mouse strains tested. It is transiently expressed at a low level during B-cell development in bone marrow on the CD45R/B220low TdT- sIg- pre-B II and CD45R/B220low TdT- sIgM+sIgD- immature B cells, but not on the CD45R/B220low TdT+ sIg- pro-B/pre-B I stage nor on CD45R/B220high TdT- sIgM+sIgD+ mature B cells. CD25 is expressed at a higher level during very early T-cell development in fetal and adult thymus. While the antibody does not block the binding of IL-2 to CD25, when used in combination with C2275-82 it results in higher levels of inhibition of IL-2-driven proliferation than either of these two monoclonal antibodies alone. Applications:  Flow cytometry 1, 3, 4, 7, 8,  Immunoprecipitation 1, 3, Recommended Dilution: Flow Cytometry: < 1ug/10e6 cells, Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Store at -20°C or colder. Aliquots are stable for at least 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Hersteller: United States Biological
Hersteller-Nr: C2275-89B

Eigenschaften

Anwendung: FC, IP
Antikörper-Typ: Monoclonal
Klon: 5K251
Konjugat: FITC
Wirt: Rat
Spezies-Reaktivität: mouse
Immunogen: IL-2-dependent BALB/c mouse helper T-cell clone HT-2
Format: Purified

Datenbank Information

Handhabung & Sicherheit

Lagerung: -20°C (frozen cool packs)
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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