Anti-CD21, clone CR2/3247

Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
NSJ-V7693-20UG 20 µg - -

3 - 10 Werktage

251,00 €
NSJ-V7693-100UG 100 µg - -

3 - 10 Werktage

541,00 €
 
0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide. Recognizes a protein of 140kDa,... mehr
Produktinformationen "Anti-CD21, clone CR2/3247"
0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide. Recognizes a protein of 140kDa, which is identified as the complement receptor 2 (CR2) or CD21. This protein is expressed strongly on mature B cells, follicular dendritic cells and weakly on immature thymocytes and T lymphocytes. In B-cell ontogeny, CD21 appears after the pre-B-stage, is maintained during peripheral B-cell development and is lost upon terminal differentiation into plasma cells. CD21 expression is also gradually lost after stimulation of B cells in vitro. CD21 functions as receptor for C3d, C3dg and iC3b Complement components, for EBV and for IFNalpha. CD21 binds to CD23 and associates with CD19, CD81 and Leu13 to form a large signal-transduction complex involved in B cell activation. Protein function: Receptor for complement C3, for the Epstein-Barr virus on human B-cells and T-cells and for HNRNPU (PubMed:7753047). Participates in B lymphocytes activation (PubMed:7753047). [The UniProt Consortium]
Schlagworte: Anti-CR2, Anti-Cr2, Anti-C3DR, Anti-CD21, Anti-EBV receptor, Anti-Complement C3d receptor, Anti-Complement receptor type 2, Anti-Epstein-Barr virus receptor, CD21 Antibody
Hersteller: NSJ Bioreagents
Hersteller-Nr: V7693-20UG

Eigenschaften

Anwendung: ELISA, IHC (paraffin)
Antikörper-Typ: Monoclonal
Klon: CR2/3247
Konjugat: No
Wirt: Mouse
Reaktivität: Human
Immunogen: A partial protein corresponding to amino acids 142-240
Format: Purified

Handhabung & Sicherheit

Lagerung: +4°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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