Anti-CD1a (T-cell Surface Glycoprotein CD1a, T-cell Surface Antigen T6/Leu-6, hTa1 Thymocyte Antigen

CD1a is a 49kD transmembrane glycoprotein in the CD1 family of glycolipid antigen-presenting MHC-like molecules. CD1a contains one Ig-like domain in its extracellular region. It is expressed by most non-human mammals but not by mice or rats. Complexes of CD1a with B2-microglobulin and endogenous glycolipids are constitutively expressed on antigen-presenting cells, cortical thymocytes, and Langerhans cells. CD1a is a target of auto reactive Th22 helper T cells in the skin. Applications: Suitable for use in Flow Cytometry. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Absorption: 620-650nm , Emission: 660-670nm, Storage and Stability: May be stored at 4°C before opening. DO NOT FREEZE! Stable at 4°C as an undiluted liquid. Dilute only prior to immediate use. Stable for 12 months. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer. APC is light sensitive.