Anti-Carboxypeptidase A1áAntibody / CPA1, clone CBPA1-1

1 mg/ml in 1X PBS, BSA free, sodium azide free. The CPA1 gene encodes Carboxypeptidase A1, a member of the carboxypeptidase A family of zinc metalloproteases. This enzyme is produced in the pancreas and preferentially cleaves C-terminal branched-chain and aromatic amino acids from dietary proteins. This gene and several family members are present in a gene cluster on chromosome 7. Mutations in this gene may be linked to chronic pancreatitis, while elevated protein levels may be associated with pancreatic cancer. [RefSeq] Protein function: Carboxypeptidase that catalyzes the release of a C- terminal amino acid, but has little or no action with -Asp, -Glu, -Arg, -Lys or -Pro. [The UniProt Consortium]