Anti-Bone Morphogenetic Protein-2 (BMP2), clone 5C15

BMP-2 is a member of the transforming growth factor beta, (TGF-b3) superfamily. It can induce bone formation and regeneration during early embryonic development. BMP-2 is synthesized as a large precursor molecule first and the mature protein is secreted by proteolytic cleavage. Natural mature BMP-2 monomer has 114 amino acid residues and has no biological function unless it turns into a dimer. It is assumed that mature BMP-2 forms a cysteine knot with seven conserved cysteine residues. The active form can consist of a dimer of two identical proteins or a heterodimer of two related bone morphogenetic proteins. Applications: Suitable for use in Indirect ELISA and Western Blot. Other applications not tested. Recommended Dilutions: Indirect ELISA: 1:250 , Optimal dilutions to be determined by the researcher. Hybridoma: Balb/c mice. Source: Ascites , Storage and Stability:, Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.