Anti-Beta Glucuronidase / Gusb

0.5mg/ml if reconstituted with 0.2ml sterile DI water. Beta-glucuronidases are members of the glycosidase family of enzymes that catalyze breakdown of complex carbohydrates. This gene encodes a hydrolase that degrades glycosaminoglycans, including heparan sulfate, dermatan sulfate, and chondroitin-4,6-sulfate. The enzyme forms a homotetramer that is localized to the lysosome. Mutations in this gene result in mucopolysaccharidosis type VII. Alternative splicing results in multiple transcript variants. There are many pseudogenes of this locus in the human genome. Protein function: Plays an important role in the degradation of dermatan and keratan sulfates. [The UniProt Consortium]