Anti-ARFGEF2

Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
ATA-HPA026078.100 100 µl -

7 - 10 Werktage*

446,00 €
 
Protein function: Promotes guanine-nucleotide exchange on ARF1 and ARF3 and to a lower extent on... mehr
Produktinformationen "Anti-ARFGEF2"
Protein function: Promotes guanine-nucleotide exchange on ARF1 and ARF3 and to a lower extent on ARF5 and ARF6. Promotes the activation of ARF1/ARF5/ARF6 through replacement of GDP with GTP. Involved in the regulation of Golgi vesicular transport. Required for the integrity of the endosomal compartment. Involved in trafficking from the trans-Golgi network (TGN) to endosomes and is required for membrane association of the AP-1 complex and GGA1. Seems to be involved in recycling of the transferrin receptor from recycling endosomes to the plasma membrane. Probably is involved in the exit of GABA(A) receptors from the endoplasmic reticulum. Involved in constitutive release of tumor necrosis factor receptor 1 via exosome-like vesicles, the function seems to involve PKA and specifically PRKAR2B. Proposed to act as A kinase-anchoring protein (AKAP) and may mediate crosstalk between Arf and PKA pathways. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 78% and to rat: 74%
Schlagworte: Anti-ARFGEF2, Anti-ARFGEP2, Anti-Brefeldin A-inhibited GEP 2, Anti-Brefeldin A-inhibited guanine nucleotide-exchange protein 2, Anti-ADP-ribosylation factor guanine nucleotide-exchange factor 2
Hersteller: Atlas Antibodies
Hersteller-Nr: HPA026078

Eigenschaften

Anwendung: WB, IHC
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Spezies-Reaktivität: human
Immunogen: Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: KPIQSKPQSP VIQAAAVSPK FVRLKHSQAQ SKPTTPEKTD LTNGEHARSD SGKVSTENGD APRERGSSLS GTDDGAQEVV KDILEDVVTS AIKAAEKHGL TEPERVLGEL ECQECAIPPG VDENSQTNGI (ATA-APrEST71270)

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +20°C (International: +20°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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