Anti-Aquaporin 4 / AQP4

Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
NSJ-R32145 100 µg - -

3 - 10 Werktage

503,00 €
 
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Aquaporin 4 is found in the basolateral... mehr
Produktinformationen "Anti-Aquaporin 4 / AQP4"
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Aquaporin 4 is found in the basolateral cell membrane of principal collecting duct cells and provides a pathway for water to exit these cells. The gene of AQP4 is mapped to 18q11.2-q12.1. Similar to other aquaporins, the AQP4 gene is composed of 4 exons encoding 127, 55, 27, and 92 amino acids separated by introns of 0.8, 0.3, and 5.2 kb. Unlike other aquaporins, an alternative coding initiation sequence (designated exon 0) was located 2.7 kb upstream of exon 1. When spliced together, M1 and the subsequent 10 amino acids are encoded by exon 0, the next 11 amino acids and M23 are encoded by exon 1. AQP4 is expressed in astrocytes and is upregulated by direct insult to the central nervous system. And AQP4 is the predominant water channel in the brain and has an important role in brain water homeostasis. It is abundant in mammalian brain and is concentrated in astrocytic foot processes at the blood-brain barrier. Protein function: Forms a water-specific channel. Osmoreceptor which regulates body water balance and mediates water flow within the central nervous system. [The UniProt Consortium]
Schlagworte: Anti-MIWC, Anti-AQP4, Anti-WCH4, Anti-AQP-4, Anti-Aquaporin-4, Anti-Mercurial-insensitive water channel, Aquaporin 4 Antibody / AQP4
Hersteller-Nr: R32145

Eigenschaften

Anwendung: WB, IHC (paraffin), IF
Antikörper-Typ: Polyclonal
Wirt: Rabbit
Reaktivität: Human, Mouse, Rat
Immunogen: Amino acids KPGVVHVIDVDRGEEKKGKDQSGEVLSSV of human Aquaporin 4 were used as the immunogen for the AQP4 antibody.
Format: Purified

Handhabung & Sicherheit

Lagerung: -20°C
Versand: -20°C (International: -20°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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