Anti-Apolipoprotein A2

This gene encodes apolipoprotein (apo-) A-II, which is the second most abundant protein of the high density lipoprotein particles. The protein is found in plasma as a monomer, homodimer, or heterodimer with apolipoprotein D. Defects in this gene may result in apolipoprotein A-II deficiency or hypercholesterolemia. Protein function: May stabilize HDL (high density lipoprotein) structure by its association with lipids, and affect the HDL metabolism. [The UniProt Consortium]