Anti-APC

Anti-APC
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
A300-980A-T 10 µl (10 µg) -

2 - 8 Werktage*

164,00 €
A300-980A 100 µl (100 µg) -

2 - 8 Werktage*

588,00 €
 
Protein function: Tumor suppressor. Promotes rapid degradation of CTNNB1 and participates in Wnt... mehr
Produktinformationen "Anti-APC"
Protein function: Tumor suppressor. Promotes rapid degradation of CTNNB1 and participates in Wnt signaling as a negative regulator. APC activity is correlated with its phosphorylation state. Activates the GEF activity of SPATA13 and ARHGEF4. Plays a role in hepatocyte growth factor (HGF)-induced cell migration. Required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells. Acts as a mediator of ERBB2-dependent stabilization of microtubules at the cell cortex. It is required for the localization of MACF1 to the cell membrane and this localization of MACF1 is critical for its function in microtubule stabilization. [The UniProt Consortium]
Schlagworte: Anti-APC, Anti-DP2.5, Anti-Protein APC, Anti-Deleted in polyposis 2.5, Anti-Adenomatous polyposis coli protein
Hersteller: Bethyl Laboratories
Hersteller-Nr: A300-980A

Eigenschaften

Anwendung: WB, IP, IHC
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Spezies-Reaktivität: human (Erwartet: bovine, dog, horse, swine, panda, orangutan, rhesus monkey, gorilla, chimpanzee, white-tufted-ear marmoset, crab-eating macaque, african elephant, small-eared galago, little brown bat, northern white-cheeked gibbon)
Immunogen: synthetic peptide. The epitope recognized by A300-980A-T maps to a region between residue 75 and 125 of human adenomatosis polyposis coli using the numbering given in entry NP_000029.2 (GeneID 324).
Format: Antigen Affinity Purified

Handhabung & Sicherheit

Lagerung: +4°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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