Anti-Anthrax PA

Anti-Anthrax PA Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with Anthrax PA from other sources has not been determined. Protein function: One of the three proteins composing the anthrax toxin, the agent which infects many mammalian species and that may cause death. PA binds to a receptor (ATR) in sensitive eukaryotic cells, thereby facilitating the translocation of the enzymatic toxin components, edema factor and lethal factor, across the target cell membrane. PA associated with LF causes death when injected, PA associated with EF produces edema. PA induces immunity to infection with anthrax. [The UniProt Consortium]