Anti-Anthrax Edema Factor

Anti-Anthrax Edema Factor Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with Anthrax Edema Factor from other sources has not been determined. Protein function: One of the three proteins composing the anthrax toxin, the agent which infects many mammalian species and that may cause death. EF is a calmodulin-dependent adenylyl cyclase that, when associated with PA, causes edema. EF is not toxic by itself and it is required for the survival of germinated spores within macrophages at the early stages of infection. Provokes dramatic elevation of intracellular cAMP levels in the host. [The UniProt Consortium]